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16-bit Microcontrollers - MCU

16-bit Microcontrollers are in stock with same-day shipping at Mouser from industry leading manufacturers. Mouser is an authorized distributor for many 16-bit microcontroller manufacturers including Infineon, Microchip, NXP, STMicroelectronics, Texas Instruments & more. Please view our large selection of 16-bit microcontrollers below.

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Image	Part #	Mfr.	Description	Datasheet	Availability	Pricing (USD) Filter the results in the table by unit price based on your quantity.	Qty.	Core	Program Memory Size	Data RAM Size	Package / Case	Maximum Clock Frequency	ADC Resolution	Number of I/Os	Supply Voltage - Min	Supply Voltage - Max	Mounting Style	Data Bus Width	Minimum Operating Temperature	Maximum Operating Temperature	Series	Qualification	Packaging
16-bit Microcontrollers - MCU 16-BIT GENERAL MCU RL78/G21 256K 44LQFP -40 to 105 C R7F103GFJ3ZFP#UA0 Renesas Electronics 1: $2.69 320In Stock New Product	Mfr. Part # R7F103GFJ3ZFP#UA0 Mouser Part # 968-R7F103GFJ3ZF#UA0 New Product	Renesas Electronics	16-bit Microcontrollers - MCU 16-BIT GENERAL MCU RL78/G21 256K 44LQFP -40 to 105 C Learn More about Renesas Electronics renesas rl78 g21 mcus	Datasheet	320In Stock	$2.69 $1.75 $1.59 $1.34 View $1.25 $1.09 $0.974 $0.954 $0.909	Min.: 1 Mult.: 1				LQFP-44						SMD/SMT				RL78/G21		Tray
16-bit Microcontrollers - MCU 16-BIT GENERAL MCU RL78/G23 Touch+ 256K 48LFQFP -40 to 105 C R7F104GGJ3CFB#UA0 Renesas Electronics 1: $5.27 500In Stock New Product	Mfr. Part # R7F104GGJ3CFB#UA0 Mouser Part # 968-R7F104GGJ3CF#UA0 New Product	Renesas Electronics	16-bit Microcontrollers - MCU 16-BIT GENERAL MCU RL78/G23 Touch+ 256K 48LFQFP -40 to 105 C Learn More about Renesas Electronics renesas rl78 g23 mcus	Datasheet	500In Stock	$5.27 $3.49 $3.18 $2.83 View $2.40 $2.29 $2.12 $2.09 $1.98	Min.: 1 Mult.: 1				LQFP-48						SMD/SMT		- 40 C	+ 105 C	RL78/G23		Tray
16-bit Microcontrollers - MCU 512KB FL 53248Bytes RAM GP PIC24EP512GP806-I/PT Microchip Technology 1: $10.03 1,750In Stock	Mfr. Part # PIC24EP512GP806-I/PT Mouser Part # 579-24EP512GP806IPT	Microchip Technology	16-bit Microcontrollers - MCU 512KB FL 53248Bytes RAM GP Learn More about Microchip Technology microchip dspic33e dscs pic24e mcus	Datasheet	1,750In Stock	$10.03 $9.18 $8.93 $8.27 $8.26	Min.: 1 Mult.: 1	PIC24E	512 kB	52 kB	TQFP-64	60 MHz	10 bit, 12 bit	53 I/O	3 V	3.6 V	SMD/SMT	16 bit	- 40 C	+ 85 C	PIC24EPxxxGP80x	AEC-Q100	Tray
16-bit Microcontrollers - MCU 16 Bit MCU 40MIPS 128KB FLASH PIC24HJ128GP506A-E/PT Microchip Technology 1: $7.87 1,995In Stock	Mfr. Part # PIC24HJ128GP506A-E/PT Mouser Part # 579-PIC24HJ128GP50PT	Microchip Technology	16-bit Microcontrollers - MCU 16 Bit MCU 40MIPS 128KB FLASH Learn More about Microchip Technology microchip 16bit mcu dsc	Datasheet	1,995In Stock	$7.87 $7.82 $7.23 $6.55 View $6.54 $6.50	Min.: 1 Mult.: 1	PIC24H	128 kB	8 kB	TQFP-64	40 MHz	10 bit, 12 bit	53 I/O	3 V	3.6 V	SMD/SMT	16 bit	- 40 C	+ 125 C	PIC24HJxxxGPx06A	AEC-Q100	Tray
16-bit Microcontrollers - MCU 16 Bit MCU, 16 MIPS 256KB Flash XLP, LCD PIC24FJ256GA410-I/PT Microchip Technology 1: $7.11 3,343In Stock	Mfr. Part # PIC24FJ256GA410-I/PT Mouser Part # 579-24FJ256GA410I/PT	Microchip Technology	16-bit Microcontrollers - MCU 16 Bit MCU, 16 MIPS 256KB Flash XLP, LCD Learn More about Microchip Technology microchip pic24fj	Datasheet	3,343In Stock	$7.11 $6.53 $5.92 $5.89	Min.: 1 Mult.: 1	PIC24F	256 kB	16 kB	TQFP-100	32 MHz	10 bit, 12 bit	85 I/O	2 V	3.6 V	SMD/SMT	16 bit	- 40 C	+ 85 C	PIC24FJxxxGA4xx		Tray
16-bit Microcontrollers - MCU PIC24F Advanced Analog XLP PIC24FJ128GC010T-I/PT Microchip Technology 1: $7.21 3,050In Stock	Mfr. Part # PIC24FJ128GC010T-I/PT Mouser Part # 579-24FJ128GC010TIPT	Microchip Technology	16-bit Microcontrollers - MCU PIC24F Advanced Analog XLP Learn More about Microchip Technology microchip pic24fj	Datasheet	3,050In Stock	Cut Tape $7.21 $7.03 $6.79 $6.74 View Reel $5.91 $6.71 $6.65 $5.91 Quote MouseReel Available	Min.: 1 Mult.: 1 : 1,200	PIC24F	128 kB	8 kB	TQFP-100	32 MHz	12 bit, 16 bit	85 I/O	2 V	3.6 V	SMD/SMT	16 bit	- 40 C	+ 85 C	PIC24FJxxxGC0xx		Reel, Cut Tape, MouseReel
16-bit Microcontrollers - MCU 144P 512KB 52KB RAM 60 MHz USB PIC24EP512GU814-I/PH Microchip Technology 1: $12.15 5,711In Stock	Mfr. Part # PIC24EP512GU814-I/PH Mouser Part # 579-PIC24EP512814IPH	Microchip Technology	16-bit Microcontrollers - MCU 144P 512KB 52KB RAM 60 MHz USB Learn More about Microchip Technology microchip dspic33e dscs pic24e mcus	Datasheet	5,711In Stock	$12.15 $12.02 $11.34 $11.33 View $10.47 $10.44	Min.: 1 Mult.: 1	PIC24E	512 kB	52 kB	TQFP-144	60 MHz	10 bit, 12 bit	122 I/O	3 V	3.6 V	SMD/SMT	16 bit	- 40 C	+ 85 C	PIC24EPxxxGU81x	AEC-Q100	Tray
16-bit Microcontrollers - MCU 16-BIT GENERAL MCU RL78/F25 512K LFQFP100 -40 to 125 C R7F125FPL4AFB-C#UA0 Renesas Electronics 1: $9.24 76In Stock New Product	Mfr. Part # R7F125FPL4AFB-C#UA0 Mouser Part # 968-7F125FPL4AFBCUA0 New Product	Renesas Electronics	16-bit Microcontrollers - MCU 16-BIT GENERAL MCU RL78/F25 512K LFQFP100 -40 to 125 C	Datasheet	76In Stock	$9.24 $6.93 $5.90 $4.91 View $4.74 $4.70 Quote	Min.: 1 Mult.: 1	RL78	16 kB	40 kB	QFP-100	80 MHz	12 bit	84 I/O	2.7 V	5.5 V	SMD/SMT	16 bit	- 40 C	+ 125 C	RL78/F25		Tray
16-bit Microcontrollers - MCU S12GC 16-bit MCU, HCS12 core, 32KB Flash, 50MHz, QFP 80 MC9S12GC32CFUE NXP Semiconductors 1: $23.12 1,017In Stock	Mfr. Part # MC9S12GC32CFUE Mouser Part # 841-MC9S12GC32CFUE	NXP Semiconductors	16-bit Microcontrollers - MCU S12GC 16-bit MCU, HCS12 core, 32KB Flash, 50MHz, QFP 80	Datasheet	1,017In Stock	$23.12 $18.08 $17.27 $15.69 View $15.16 $14.81 Quote	Min.: 1 Mult.: 1	HCS12	32 kB	2 kB	PQFP-80	25 MHz	10 bit	60 I/O	2.35 V	2.75 V	SMD/SMT	16 bit	- 40 C	+ 85 C	S12GC		Tray
16-bit Microcontrollers - MCU 16-bit PIC24F, 16 MIPS, 128KB Flash, 16KB RAM, 28 pin PIC24FJ128GA702-I/MV Microchip Technology 1: $1.83 9,794In Stock	Mfr. Part # PIC24FJ128GA702-I/MV Mouser Part # 579-24FJ128GA702IMV	Microchip Technology	16-bit Microcontrollers - MCU 16-bit PIC24F, 16 MIPS, 128KB Flash, 16KB RAM, 28 pin Learn More about Microchip Technology microchip pic24fj	Datasheet	9,794In Stock	$1.83 $1.66 $1.51	Min.: 1 Mult.: 1	PIC24F	128 kB	16 kB	UQFN-28	32 MHz	10 bit, 12 bit	22 I/O	2 V	3.6 V	SMD/SMT	16 bit	- 40 C	+ 85 C	PIC24FJxxxGA70x		Tube
16-bit Microcontrollers - MCU 64KB FL 8192b RAM 16MIPS 21I/O 16b Fam PIC24FJ64GA002-I/ML Microchip Technology 1: $3.99 12,026In Stock	Mfr. Part # PIC24FJ64GA002-I/ML Mouser Part # 579-PIC24FJ64A002IML	Microchip Technology	16-bit Microcontrollers - MCU 64KB FL 8192b RAM 16MIPS 21I/O 16b Fam Learn More about Microchip Technology microchip pic24fj	Datasheet	12,026In Stock	$3.99 $3.91	Min.: 1 Mult.: 1	PIC24F	64 kB	8 kB	QFN-28	32 MHz	10 bit	21 I/O	2 V	3.6 V	SMD/SMT	16 bit	- 40 C	+ 85 C	PIC24FJxxGA00x	AEC-Q100	Tube
16-bit Microcontrollers - MCU Mixed Signal MCU A 5 95-MSP430FR5729IDA A 595-MSP430FR5729IDA MSP430FR5729IDAR Texas Instruments 1: $6.66 9,478In Stock	Mfr. Part # MSP430FR5729IDAR Mouser Part # 595-MSP430FR5729IDAR	Texas Instruments	16-bit Microcontrollers - MCU Mixed Signal MCU A 5 95-MSP430FR5729IDA A 595-MSP430FR5729IDA Learn More about Texas Instruments timsp430fr57xx	Datasheet	9,478In Stock	Cut Tape $6.66 $4.58 $4.27 $3.75 Reel $2.72 View $3.56 $3.20 $2.94 $2.67 MouseReel Available	Min.: 1 Mult.: 1 : 2,000	MSP430	16 kB	1 kB	TSSOP-38	8 MHz	10 bit	30 I/O	2 V	3.6 V	SMD/SMT	16 bit	- 40 C	+ 85 C	MSP430FR5729		Reel, Cut Tape, MouseReel
16-bit Microcontrollers - MCU S12DJ 16-bit MCU, HCS12 core, 256KB Flash, QFP 80 MC9S12DJ256MFUE NXP Semiconductors 1: $67.09 409In Stock	Mfr. Part # MC9S12DJ256MFUE Mouser Part # 841-MC9S12DJ256MFUE	NXP Semiconductors	16-bit Microcontrollers - MCU S12DJ 16-bit MCU, HCS12 core, 256KB Flash, QFP 80	Datasheet	409In Stock	$67.09 $57.00 $54.84 $52.30	Min.: 1 Mult.: 1	HCS12	256 kB	12 kB	PQFP-80	25 MHz	2 x 10 bit	59 I/O	2.35 V	2.75 V	SMD/SMT	16 bit	- 40 C	+ 125 C	S12D		Tray
16-bit Microcontrollers - MCU S12XD 16-bit MCU, HCS12X core, 512KB Flash, 80MHz, QFP 112 MC9S12XDP512VAL NXP Semiconductors 1: $56.07 512In Stock	Mfr. Part # MC9S12XDP512VAL Mouser Part # 841-MC9S12XDP512VAL	NXP Semiconductors	16-bit Microcontrollers - MCU S12XD 16-bit MCU, HCS12X core, 512KB Flash, 80MHz, QFP 112	Datasheet	512In Stock	$56.07 $46.77 $44.35 $41.85 View Quote	Min.: 1 Mult.: 1	HCS12X	512 kB	32 kB	LQFP-112	80 MHz	10 bit	59 I/O	2.35 V	2.75 V	SMD/SMT	16 bit	- 40 C	+ 105 C	S12XD		Tray
16-bit Microcontrollers - MCU 16-bit MCU, S12X core, 1MB Flash, 50MHz, -40/+125degC, QFP 144 MC9S12XEP100MAG NXP Semiconductors 1: $54.06 809In Stock	Mfr. Part # MC9S12XEP100MAG Mouser Part # 841-MC9S12XEP100MAG	NXP Semiconductors	16-bit Microcontrollers - MCU 16-bit MCU, S12X core, 1MB Flash, 50MHz, -40/+125degC, QFP 144	Datasheet	809In Stock	$54.06 $45.28 $42.77 $40.76 View Quote	Min.: 1 Mult.: 1	HCS12X	1 MB	64 kB	LQFP-144	50 MHz	2 x 8 bit/10 bit/12 bit	119 I/O	1.72 V	1.98 V	SMD/SMT	16 bit	- 40 C	+ 125 C	S12XE	AEC-Q100	Tray
16-bit Microcontrollers - MCU 16-BIT GENERAL MCU RL78/G12 16K 30LSSOP -40 to 85 C R5F102AAASP#50 Renesas Electronics 1: $1.29 393,944In Stock	Mfr. Part # R5F102AAASP#50 Mouser Part # 968-R5F102AAASP#50	Renesas Electronics	16-bit Microcontrollers - MCU 16-BIT GENERAL MCU RL78/G12 16K 30LSSOP -40 to 85 C Learn More about Renesas Electronics renesas rl78 mcu	Datasheet	393,944In Stock	Cut Tape $1.29 $1.13 $0.911 $0.857 View Reel $0.661 $0.824 $0.796 $0.661 MouseReel Available	Min.: 1 Mult.: 1 : 2,500	RL78	16 kB	2 kB	LSSOP-30	24 MHz	8 bit/10 bit	26 I/O	1.8 V	5.5 V	SMD/SMT	16 bit	- 40 C	+ 85 C	RL78/G12		Reel, Cut Tape, MouseReel
16-bit Microcontrollers - MCU 16-BIT GENERAL MCU_RL78/F13_64KB 20SSOP R5F10A6ELSP#U5 Renesas Electronics 1: $4.16 6,979In Stock	Mfr. Part # R5F10A6ELSP#U5 Mouser Part # 968-R5F10A6ELSP#U5	Renesas Electronics	16-bit Microcontrollers - MCU 16-BIT GENERAL MCU_RL78/F13_64KB 20SSOP Learn More about Renesas Electronics renesas rl78 f13 mcus	Datasheet	6,979In Stock	$4.16 $3.14 $2.74 $2.48 View $2.47 $2.35 $2.28 $2.26 $2.21	Min.: 1 Mult.: 1	RL78	64 kB	4 kB	SSOP-20	32 MHz	10 bit	13 I/O	2.7 V	5.5 V	SMD/SMT	16 bit	- 40 C	+ 105 C	RL78/F13	AEC-Q100	Tray
16-bit Microcontrollers - MCU 16-Bit, 16 MIPS, 256KB ECC Flash, 32KB RAM, LCD, 100-pin PIC24FJ256GL410-I/PT Microchip Technology 1: $3.66 4,019In Stock	Mfr. Part # PIC24FJ256GL410-I/PT Mouser Part # 579-24FJ256GL410IPT	Microchip Technology	16-bit Microcontrollers - MCU 16-Bit, 16 MIPS, 256KB ECC Flash, 32KB RAM, LCD, 100-pin Learn More about Microchip Technology microchip pic24fj gu4gl4 mcus	Datasheet	4,019In Stock	$3.66 $3.44 $3.31	Min.: 1 Mult.: 1	PIC24F	256 kB	32 kB	TQFP-100	32 MHz	10 bit, 12 bit	86 I/O	2 V	3.6 V	SMD/SMT	16 bit	- 40 C	+ 85 C	PIC24FJ		Tray
16-bit Microcontrollers - MCU 16b 256KB Flash 96K RAM USB PIC24FJ256GB206T-I/PT Microchip Technology 1: $8.73 3,315In Stock	Mfr. Part # PIC24FJ256GB206T-I/PT Mouser Part # 579-PIC24FJ256G20IPT	Microchip Technology	16-bit Microcontrollers - MCU 16b 256KB Flash 96K RAM USB Learn More about Microchip Technology microchip pic24fj	Datasheet	3,315In Stock	Cut Tape $8.73 $8.53 $8.52 $8.51 View Reel $7.24 $8.09 $7.24 Quote MouseReel Available	Min.: 1 Mult.: 1 : 1,200	PIC24F	256 kB	96 kB	TQFP-64	32 MHz	10 bit	52 I/O	2 V	3.6 V	SMD/SMT	16 bit	- 40 C	+ 85 C	PIC24FJxxxGB2xx		Reel, Cut Tape, MouseReel
16-bit Microcontrollers - MCU 32 kB Flash 1KB RAM 12b ADC-2 USART-HW A A 595-430F147IPM MSP430F147IPMR Texas Instruments 1: $15.57 2,473In Stock 1,000Expected 1/7/2027	Mfr. Part # MSP430F147IPMR Mouser Part # 595-430F147IPMR	Texas Instruments	16-bit Microcontrollers - MCU 32 kB Flash 1KB RAM 12b ADC-2 USART-HW A A 595-430F147IPM Learn More about Texas Instruments ti msp430 mcus	Datasheet	2,473In Stock 1,000Expected 1/7/2027	Cut Tape $15.57 $12.30 $10.99 $10.58 View Reel $9.66 $10.44 $10.04 $9.66 Quote MouseReel Available	Min.: 1 Mult.: 1 : 1,000	MSP430	32 kB	1 kB	LQFP-64	8 MHz	12 bit	48 I/O	1.8 V	3.6 V	SMD/SMT	16 bit	- 40 C	+ 85 C	MSP430F147		Reel, Cut Tape, MouseReel
16-bit Microcontrollers - MCU 16-bit Ultra-Lo-Pwr Microcontroller A 59 A 595-MSP430F2272IDAR MSP430F2272IDA Texas Instruments 1: $9.63 4,862In Stock	Mfr. Part # MSP430F2272IDA Mouser Part # 595-MSP430F2272IDA	Texas Instruments	16-bit Microcontrollers - MCU 16-bit Ultra-Lo-Pwr Microcontroller A 59 A 595-MSP430F2272IDAR Learn More about Texas Instruments ti msp430 mcus	Datasheet	4,862In Stock	$9.63 $8.44 $6.44 $6.29 View $5.90 $5.76 Quote	Min.: 1 Mult.: 1	MSP430	32 kB	1 kB	TSSOP-38	16 MHz	10 bit	32 I/O	1.8 V	3.6 V	SMD/SMT	16 bit	- 40 C	+ 105 C	MSP430F2272		Tube
16-bit Microcontrollers - MCU 16-bit Ultra-Lo-Pwr Microcontroller A 59 A 595-MSP430F2272IRHAR MSP430F2272IRHAT Texas Instruments 1: $10.36 2,582In Stock	Mfr. Part # MSP430F2272IRHAT Mouser Part # 595-MSP430F2272IRHAT	Texas Instruments	16-bit Microcontrollers - MCU 16-bit Ultra-Lo-Pwr Microcontroller A 59 A 595-MSP430F2272IRHAR Learn More about Texas Instruments ti msp430 mcus	Datasheet	2,582In Stock	Cut Tape $10.36 $8.07 $7.16 $6.87 Reel $6.56 View $6.23 Quote MouseReel Available	Min.: 1 Mult.: 1 : 250	MSP430	32 kB	1 kB	VQFN-40	16 MHz	10 bit	32 I/O	1.8 V	3.6 V	SMD/SMT	16 bit	- 40 C	+ 105 C	MSP430F2272		Reel, Cut Tape, MouseReel
16-bit Microcontrollers - MCU 16-bit MCU, S12X core, 1MB Flash, 50MHz, -40/+125degC, QFP 112 MC9S12XEP100MAL NXP Semiconductors 1: $53.92 407In Stock	Mfr. Part # MC9S12XEP100MAL Mouser Part # 841-MC9S12XEP100MAL	NXP Semiconductors	16-bit Microcontrollers - MCU 16-bit MCU, S12X core, 1MB Flash, 50MHz, -40/+125degC, QFP 112	Datasheet	407In Stock	$53.92 $45.66 $42.64 $40.83 View $39.54 Quote	Min.: 1 Mult.: 1	HCS12X	1 MB	64 kB	LQFP-112	50 MHz	2 x 8 bit/10 bit/12 bit	91 I/O	1.72 V	1.98 V	SMD/SMT	16 bit	- 40 C	+ 125 C	S12XE	AEC-Q100	Tray
16-bit Microcontrollers - MCU 16b Fam 16MIPS 16KB FL 4096b RAM 35 I/O PIC24FJ16GA004-I/ML Microchip Technology 1: $3.65 5,160In Stock	Mfr. Part # PIC24FJ16GA004-I/ML Mouser Part # 579-PIC24FJ16A004IML	Microchip Technology	16-bit Microcontrollers - MCU 16b Fam 16MIPS 16KB FL 4096b RAM 35 I/O Learn More about Microchip Technology microchip pic24fj	Datasheet	5,160In Stock	$3.65 $3.34 $3.33 $3.04 View $3.03 $3.01 $2.95 $2.92	Min.: 1 Mult.: 1	PIC24F	16 kB	4 kB	QFN-44	32 MHz	10 bit	35 I/O	2 V	3.6 V	SMD/SMT	16 bit	- 40 C	+ 85 C	PIC24FJxxGA00x	AEC-Q100	Tube
16-bit Microcontrollers - MCU 16 MHz MCU with 256K B FRAM 8KB SRAM LE A 595-SP430FR5994IRGZT MSP430FR5994IRGZR Texas Instruments 1: $11.19 2,330In Stock	Mfr. Part # MSP430FR5994IRGZR Mouser Part # 595-P430FR5994IRGZR	Texas Instruments	16-bit Microcontrollers - MCU 16 MHz MCU with 256K B FRAM 8KB SRAM LE A 595-SP430FR5994IRGZT Learn More about Texas Instruments ti msp430fr599 msp430fr596	Datasheet	2,330In Stock	Cut Tape $11.19 $8.74 $7.76 $7.46 View Reel $6.60 $7.02 $6.77 $6.60 Quote MouseReel Available	Min.: 1 Mult.: 1 : 2,500	MSP430	256 kB	8 kB	VQFN-48	16 MHz	12 bit	40 I/O	1.8 V	3.6 V	SMD/SMT	16 bit	- 40 C	+ 85 C	MSP430FR5994		Reel, Cut Tape, MouseReel